Enter terms Preoperative skin antiseptic for prevention of surgical wound infections after clean surgery Patients' skin at the operation site is routinely cleansed with antiseptic solutions in the operating theatre before surgical incisions are made. This skin cleansing with an antiseptic aims to reduce the microorganisms present on the skin and therefore reduce the risk that the surgical wound will become infected. It is not known whether one antiseptic treatment is better than any other s at preventing infection, so our team examined the evidence for antiseptic skin preparation prior to clean surgery i.
Chlorhexidine-alcohol versus povidone-iodine as preoperative skin preparation to prevent surgical site infection: Surgical site infection remains substantial problems to surgeons and patients as it increases the morbidity, mortality, length of stay, hospital cost, rate of re-admission, and rate of re-surgery.
This study aims to compare the use of chlorhexidine-alcohol versus povidone-iodine for preoperative skin preparation to prevent surgical site infection.
The literature search was conducted through the PubMed database on November Included studies were RCTs with the year of publication up to which compared the use of chlorhexidine-alcohol versus povidone-iodine in its effectiveness reducing surgical site infection in adult patients. The quality of the study was assessed using Jadad Score.
A meta-analysis was conducted in the included study to obtain a pooled estimate of the effect size.
The evidence of heterogeneity and publication bias was also assessed. Six RCTs with a total of 2, patients were included in the meta-analysis. Preoperative skin antisepsis with chlorhexidine is more effective than povidone-iodine in preventing surgical site infection.
Keywords chlorhexidine-alcohol; povidone-iodine; skin antisepsis; surgical site infection Full Text: Guideline for prevention of surgical site infection, Hospital infection control practices advisory committee. Infect Control Hosp Epidemiol. A comparison of chlorhexidine-alcohol versus povidone-iodine for eliminating skin flora before genitourinary prosthetic surgery: Antiseptic effectiveness with fibroblast preservation.
Efficacy and safety of povidone-iodine underscored. Thyrotoxicosis induced by topical iodine application. DuraPrep surgical solution iodine povacrylex [0. Analyses comparing the antimicrobial activity and safety of current antiseptics: WHO guidelines on hand hygiene in health care: Ann Burns Fire Disasters.
Chlorhexidine--pharmacology and clinical applications. N Engl J Med.
Systematic review and meta-analysis of preoperative antisepsis with chlorhexidine versus povidone-iodine in clean-contaminated surgery. Guidelines for the prevention of intravascular catheter-related infections. Assessing the quality of reports of randomized control trials: Paocharoen, V., Mingmalairak, C., and Apisarnthanarak, A.
Comparison of surgical wound infection after preoperative skin preparation with 4% chlorhexidine [correction of chlohexidine] and povidone iodine: a prospective randomized trial.
A Trusted Partner for Healthcare Professional Chlorhexidine Gluconate 4% (Hexene Skin Cleanser Fl Oz.) Antimicrobial, Effective Defense for Preventing the Spread of .
Most of the evidence assessments in surgical skin prep have been done with chlorhexidine plus alcohol (i.e. two agents) versus povidone-iodine alone (i.e.
one agent). The question of chlorhexidine-alcohol versus iodine-alcohol is unresolved. The newest addition to the Cardinal Health™ LiquiBand® Family of topical skin adhesives includes a high-strength 2-octyl cyanoacrylate formula in the signature LiquiBand® Winged Applicator.
This combination creates an intuitive platform for effective wound closure. Chlorhexidine-alcohol versus povidone-iodine as preoperative skin preparation to prevent surgical site infection: a meta-analysis. Antiseptic for use as surgical hand scrub, healthcare personnel hand wash, patient preoperative skin preparation, and skin wound and general cleansing.